Method Development
Our Approach
We follow a systematic, data-driven approach to ensure your methods are precise, scalable, and publication- or submission-ready.
1. Project Consultation
We begin by understanding your scientific question, sample type, and analytical or preparative goals.
2. Feasibility Assessment
We assess instrumentation, expected challenges, and timelines to determine the best approach.
3. Experimental Design
Our team designs method parameters aligned with your target application and analyte properties.
4. Method Development & Optimization
We conduct stepwise experiments, adjusting variables (e.g., solvent systems, detection conditions, synthesis steps) for optimal performance.
5. Validation & Documentation
We validate the method for accuracy, precision, reproducibility, and robustness, delivering full documentation for regulatory or academic submission.
Analytical Techniques We Support
We apply cutting-edge instrumentation and expert interpretation to a wide range of techniques:
HPLC (High-Performance Liquid Chromatography)
Gradient optimization, retention time control, and detection strategies.
Mass Spectrometry (MS)
Small molecule quantitation, fragmentation analysis, structural confirmation.
NMR Spectroscopy
Structural elucidation, purity assessment.
UV-Vis Spectroscopy
Absorbance-based quantification, kinetic measurements.
Fluorescence Spectroscopy
Sensitive detection for biomolecules and dynamic interactions.
Synthetic and Preparative Capabilities
In addition to analytical methods, Synthovia offers expertise in:
Organic Synthesis
Custom compound synthesis, reaction optimization, scale-up support.
Purification and Separation
Chromatographic and preparative strategies for isolating target molecules.
Process Optimization
Efficiency improvements for reaction yield, product purity, and throughput.
Need a method built from scratch—or an existing one optimized for publication or production? Contact us today to collaborate.
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